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No. There's numerous reasons why it didn't kill straight away. If only there was some kind of way of finding out.
Wait.
Myth busting: Why didn't the Skripals die on the spot?
Nerve agents only really work quickly when they are inhaled. The mechanism of action in the Skripal case appears to be dermal absorption – the agent got into their systems through the skin. This works slowly. Signs and symptoms progress from localised ones at the site of exposure to central ones over a period of hours. In a cold war-era study with goats and the nerve agent Soman, death took up to 48 hours after exposure to the shaved skin. It's not exactly fast.
Second, if something happened to reduce the intended dose - for instance if the person opening a door handle was wearing gloves - then a possibly quite lethal dose could have been mitigated to a lower one.
In addition, we must also allow for human factors. Did one of the Skripals say: "What is this muck on my hands? I'm going to wash up". That would have initiated a self-decontamination effort. Soap and water is actually quite good at decontaminating nerve agents, as numerous studies have indicated. All of the organophosphate nerve agents degrade in the presence of water, through a mechanism called hydrolysis. So, did the door handle in question get wet? Salisbury is not known for an arid climate.
Practical toxicity in the field differs greatly from the theoretical toxicity of poisons in laboratory conditions. Every major nerve agent incident (Tokyo, Halabja, Ghouta, Khan Sheikhoun etc) has had more people injured than killed. The Tokyo incident killed 12 people, but there were nearly 70 with major exposure who survived and nearly a thousand with minor to moderate exposure.
The most important thing to consider, however, is the nature of the lethality and toxicity estimates for nerve agents. All of these toxicological statistics are derived from studies wherein the targets (almost always lab animals) did not receive decontamination or treatment for their injuries. Indeed, if you were trying to experimentally determine figures for lethality, administering antidote therapy or decontamination would warp the results and be bad science. Statements that 'substance X is five times more lethal than Y' are only valid in the absence of medical treatment. |
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