With a roof-rack, it's the vibration of the cross-bars, like a guitar string, that causes the noise.
Roof box is a carefully-considered wedge shape, i wouldn't expect excess noise from one, though it will still adversely impact fuel economy.
What are you fitting the box to? you'll need some sort of rack or roof bars to fit the box to. Make sure they are aerodynamic and the box should be fine.
Thanks everyone, sounds as if they are not a problem, I don't drive over 80mph anymore
It was the 1970's when I had the roof rack fitted to my car, so things have probably improved a bit since then
I am thinking of fitting one onto my wife's Nissan Note to save buying a bigger car that will only be needed a few times a year, she keeps forgetting that I am saving up for a Caterham 7 for us